recombinant human SCCA 1 (rhSCCA1, rhB3)
Member of the Ov-serpin family. Regulates apoptosis, cellular chemotaxis and epidermal barrier function [1,2]. Potent cross-class inhibitor of mammalian, bacterial and parasite cysteine proteinases (e.g. cathepsins L,S,K; staphopains cruzain and CPB2.8) [3,4]. May also function as a receptor for the hepatitis B virus [5].
1. Vidalino et al. Autoimmun Rev. 2009. 9(2):108-12, 2. Katagiri et al. J Dermatol Sci. 2010. 57(2): 95-101, 3. Schick et al. Biochemistry. 1998. 37(15): 5258-66, 4. Kanaji et al. FEBS Lett. 2007. 581(22): 4260-4, 5. Kasuya et al. FEBS J. 2008. 275(22): 5714-24, 6. Kantyka et al. J Biol Chem. 2011. 392(5): 483-9.
Product Specification
Safety Data Sheet