Alpha 1-antitrypsin, human plasma; Oxidized
Product Description
Alpha 1-antitrypsin, human plasma; oxidized by N-Chlorosuccinimide.
Conversion of Methionine 358 in the RSL of alpha 1-antitrypsin (AAT) to methionine sulphoxide alters the reaction rates of AAT with proteases and may convert the molecule into a pro-inflammatory stimulus [1, 2].
1. Johnson and Travis. 1979. J Biol Chem. 254(10):4022-6. PMiD: 312289; 2. Li et al. 2009. Am J Lung Cell Mol Physiol. 297(2): L388-L400. PMiD: 2742802
Product Specification
Safety Data Sheet
Conversion of Methionine 358 in the RSL of alpha 1-antitrypsin (AAT) to methionine sulphoxide alters the reaction rates of AAT with proteases and may convert the molecule into a pro-inflammatory stimulus [1, 2].
1. Johnson and Travis. 1979. J Biol Chem. 254(10):4022-6. PMiD: 312289; 2. Li et al. 2009. Am J Lung Cell Mol Physiol. 297(2): L388-L400. PMiD: 2742802
Product Specification Safety Data Sheet